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KMID : 1207720140060030358
Clinics in Orthopedic Surgery
2014 Volume.6 No. 3 p.358 ~ p.360
Spontaneous Acetabular Periprosthetic Fracture in a Patient Continuously Having Zoledronic Acid
Tantavisut Saran

Tanavalee Aree
Thanakit Voranuch
Ngarmukos Srihatach
Wilairatana Vajara
Wangroongsub Yongsak
Abstract
Zoledronic acid has been used for prevention of osteolytic and osteoblastic bone metastasis. This case report illustrates an undesirable consequence from prolonged usage of zoledronic acid in bone metastasis prevention. Periprosthetic acetabular fracture in a patient treated with zoledronic acid for 7 years was reported. The clinical presentation, radiographic and pathological results were described. This is a rare complication after total hip arthroplasty which should not be ignored especially in patients who received long term bisphosphonate.
KEYWORD
Hip arthroplasty, Fracture, Loosening, Zoledronic acid, Bisphosphonate
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